Research brief · Cognitive
Semax
ACTH(4-10) analogue used in BDNF and cognitive performance research.
Class
ACTH(4-10) analogue (heptapeptide)
Half-life
Short (intranasal)
Studied in
Neuroprotection and cognitive performance studies.
What it is
Semax is a synthetic heptapeptide analogue of ACTH(4-10) developed in Russia and studied in neuroprotection and cognitive performance research models.
Mechanism studied
Modulates BDNF and dopamine/serotonin signaling.
Research notes
- Most published clinical work originates from Russian-language literature.
Before sourcing any material
- Confirm a lot-matched third-party certificate of analysis (HPLC purity and mass-spectrometry identity).
- Check the stated peptide content per vial, not just the gross vial mass.
- Plan reconstitution volumes first so the vial size matches your protocol.
- Verify what is lawful in your jurisdiction — these are in-vitro research reagents, not medicines.