Research brief · Growth Hormone
AOD-9604
hGH C-terminal fragment used in adipose lipolysis and body-composition research.
Class
Modified hGH(177-191) C-terminal fragment
Half-life
~30 min (systemic)
Studied in
Adipose lipolysis, fat-metabolism and body-composition research.
What it is
AOD-9604 is a 16-amino-acid synthetic fragment based on the C-terminus of human growth hormone (residues 177-191) with an added tyrosine. In laboratory research it is studied as a putative lipolytic agent that engages adipose β3-adrenergic and HSL pathways without binding the GH receptor.
Mechanism studied
C-terminal hGH fragment hypothesised to mimic the lipolytic domain of growth hormone without affecting IGF-1.
Research notes
- Does not raise IGF-1 in published rodent work — useful as a GH-axis-sparing lipolytic probe.
- Often combined with GH secretagogues in comparative fat-metabolism panels.
Before sourcing any material
- Confirm a lot-matched third-party certificate of analysis (HPLC purity and mass-spectrometry identity).
- Check the stated peptide content per vial, not just the gross vial mass.
- Plan reconstitution volumes first so the vial size matches your protocol.
- Verify what is lawful in your jurisdiction — these are in-vitro research reagents, not medicines.