Research brief · Regenerative
GHK-Cu
Copper-binding tripeptide widely studied in skin and hair biology.
Class
Copper-binding tripeptide
Half-life
Short (minutes systemic)
Studied in
Skin remodeling, hair follicle biology, wound studies.
What it is
GHK-Cu is a naturally occurring copper-binding tripeptide that acts as a copper(II) chaperone, modulating ECM remodelling, antioxidant defence genes and dermal fibroblast activity.
Mechanism studied
Copper chaperone modulating ECM and antioxidant gene expression.
Research notes
- Studied as a cosmetic-grade topical powder as well as an injectable research form.
- Mix with a hyaluronic acid serum and apply topically — cosmetic use only.
- Frequently cited in cosmetic-science and wound-healing literature.
Before sourcing any material
- Confirm a lot-matched third-party certificate of analysis (HPLC purity and mass-spectrometry identity).
- Check the stated peptide content per vial, not just the gross vial mass.
- Plan reconstitution volumes first so the vial size matches your protocol.
- Verify what is lawful in your jurisdiction — these are in-vitro research reagents, not medicines.