Research brief · Longevity
Humanin
Mitochondrial-derived cytoprotective peptide for ageing research.
Class
24-aa mitochondrial-derived peptide
Half-life
Short
Studied in
Cellular stress and aging models.
What it is
Humanin is a 24-amino-acid mitochondrial-derived peptide with cytoprotective activity mediated via STAT3 signalling and IGFBP-3 binding, used in cellular stress and ageing research.
Mechanism studied
Cytoprotective via STAT3 and IGFBP-3 binding.
Research notes
- Often examined alongside MOTS-c in mitochondrial peptide panels.
Before sourcing any material
- Confirm a lot-matched third-party certificate of analysis (HPLC purity and mass-spectrometry identity).
- Check the stated peptide content per vial, not just the gross vial mass.
- Plan reconstitution volumes first so the vial size matches your protocol.
- Verify what is lawful in your jurisdiction — these are in-vitro research reagents, not medicines.