Research brief · Hormone
Kisspeptin-10
Decapeptide KISS1R agonist for HPG-axis research.
Class
GPR54/KISS1R agonist decapeptide
Half-life
~4 min
Studied in
HPG-axis activation and reproductive neuroendocrinology research.
What it is
Kisspeptin-10 is the minimal C-terminal active fragment of kisspeptin, the upstream regulator of GnRH neurons via KISS1R/GPR54. Used in HPG-axis research.
Mechanism studied
Activates KISS1R on GnRH neurons to drive LH/FSH release.
Research notes
- Frequently used as a tool to probe upstream control of GnRH neurons.
Before sourcing any material
- Confirm a lot-matched third-party certificate of analysis (HPLC purity and mass-spectrometry identity).
- Check the stated peptide content per vial, not just the gross vial mass.
- Plan reconstitution volumes first so the vial size matches your protocol.
- Verify what is lawful in your jurisdiction — these are in-vitro research reagents, not medicines.