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Research brief · Immune

LL-37

Human cathelicidin used in antimicrobial and immunity research.

Class

Cathelicidin antimicrobial peptide

Half-life

Short

Studied in

Antimicrobial and biofilm research.

What it is

LL-37 is the only human cathelicidin antimicrobial peptide, with broad-spectrum membrane-disrupting activity and immunomodulatory roles in innate defence research.

Mechanism studied

Disrupts microbial membranes; modulates innate immunity.

Research notes

  • Studied extensively in biofilm disruption research.

Before sourcing any material

  • Confirm a lot-matched third-party certificate of analysis (HPLC purity and mass-spectrometry identity).
  • Check the stated peptide content per vial, not just the gross vial mass.
  • Plan reconstitution volumes first so the vial size matches your protocol.
  • Verify what is lawful in your jurisdiction — these are in-vitro research reagents, not medicines.
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