Research brief · Growth Hormone
MK-677
Oral ghrelin mimetic for long-duration GH/IGF-1 research.
Class
Oral ghrelin mimetic (non-peptide)
Half-life
~24 h
Studied in
Long-duration GH/IGF-1 elevation studies.
What it is
MK-677 (ibutamoren) is a non-peptide, orally bioavailable ghrelin receptor agonist used in long-duration GH/IGF-1 elevation research where parenteral dosing is impractical.
Mechanism studied
Orally bioavailable GHS-R agonist.
Research notes
- Not a peptide; included for mechanistic completeness.
Before sourcing any material
- Confirm a lot-matched third-party certificate of analysis (HPLC purity and mass-spectrometry identity).
- Check the stated peptide content per vial, not just the gross vial mass.
- Plan reconstitution volumes first so the vial size matches your protocol.
- Verify what is lawful in your jurisdiction — these are in-vitro research reagents, not medicines.