Research brief · Cognitive
Semax + Selank
Neurotrophic + anxiolytic Russian neuropeptide research blend.
Class
ACTH(4-10)/tuftsin-derived neuropeptide blend
Half-life
Short (minutes, intranasal research)
Studied in
Anxiolytic, neurotrophic and cognitive-research models.
What it is
This blend pairs semax (a heptapeptide ACTH(4-10) analogue) with selank (a tuftsin analogue). In research it is used to study combined neurotrophic and anxiolytic endpoints in cognitive-pathway models.
Mechanism studied
Combined BDNF/NGF upregulation (semax) and GABAergic / anxiolytic modulation (selank).
Research notes
- Common intranasal research model for combined BDNF and GABAergic endpoints.
- Frequently benchmarked against PE-22-28 in mood-pathway panels.
Before sourcing any material
- Confirm a lot-matched third-party certificate of analysis (HPLC purity and mass-spectrometry identity).
- Check the stated peptide content per vial, not just the gross vial mass.
- Plan reconstitution volumes first so the vial size matches your protocol.
- Verify what is lawful in your jurisdiction — these are in-vitro research reagents, not medicines.