Research brief · Performance
SS-31
Mitochondria-targeted tetrapeptide for cardiolipin/ETC research.
Class
Mitochondria-targeted tetrapeptide
Half-life
~2 h
Studied in
Mitochondrial dysfunction models.
What it is
SS-31 (elamipretide) is a mitochondria-targeted tetrapeptide that binds cardiolipin in the inner mitochondrial membrane, supporting cristae architecture and electron transport efficiency in research models.
Mechanism studied
Binds cardiolipin to stabilize inner mitochondrial membrane.
Research notes
- Used in studies of cardiac and skeletal muscle mitochondrial dysfunction.
Before sourcing any material
- Confirm a lot-matched third-party certificate of analysis (HPLC purity and mass-spectrometry identity).
- Check the stated peptide content per vial, not just the gross vial mass.
- Plan reconstitution volumes first so the vial size matches your protocol.
- Verify what is lawful in your jurisdiction — these are in-vitro research reagents, not medicines.