Research brief · Growth Hormone
Tesamorelin + Ipamorelin
GHRH analogue + selective ghrelin-agonist blend for visceral-adipose and GH-pulse studies.
Class
Stabilised GHRH analogue + selective ghrelin-receptor agonist blend
Half-life
~26 min (tesamorelin) / ~2 h (ipamorelin)
Studied in
Visceral-adipose, lipid and GH-pulse research models.
What it is
Tesamorelin + Ipamorelin pairs a stabilised GHRH analogue (tesamorelin) with a selective ghrelin-receptor agonist (ipamorelin). In research the blend is used to study GH pulse synergy with a particular interest in visceral-adipose endpoints driven by the tesamorelin arm.
Mechanism studied
Combined GHRH-receptor and GHS-R1a agonism for synergistic GH pulse amplitude.
Research notes
- Tesamorelin's published rodent work emphasises VAT-selective lipolysis endpoints.
- Ipamorelin keeps the cortisol/prolactin profile clean for comparative analyses.
Before sourcing any material
- Confirm a lot-matched third-party certificate of analysis (HPLC purity and mass-spectrometry identity).
- Check the stated peptide content per vial, not just the gross vial mass.
- Plan reconstitution volumes first so the vial size matches your protocol.
- Verify what is lawful in your jurisdiction — these are in-vitro research reagents, not medicines.