Research brief · Immune
VIP
Secretin-family neuropeptide for immune and vascular research.
Class
28-aa secretin-family peptide
Half-life
~2 min (plasma)
Studied in
Immunomodulation, vascular tone and circadian research models.
What it is
VIP is a 28-amino-acid secretin-family neuropeptide signalling through VPAC1 and VPAC2 receptors. Research applications include immunomodulation, vascular biology and circadian rhythm models.
Mechanism studied
Agonist at VPAC1/VPAC2 receptors; broad immunomodulatory and vasodilator activity.
Research notes
- Very short plasma half-life — research designs use acute or controlled exposure.
Before sourcing any material
- Confirm a lot-matched third-party certificate of analysis (HPLC purity and mass-spectrometry identity).
- Check the stated peptide content per vial, not just the gross vial mass.
- Plan reconstitution volumes first so the vial size matches your protocol.
- Verify what is lawful in your jurisdiction — these are in-vitro research reagents, not medicines.