Protocols · Metabolic
GLP1 is the research code name for semaglutide, sold as Ozempic and Wegovy. This page covers that one compound only, so the reported figures cannot be confused with the dual or triple agonists. Every published programme uses a stepped escalation design rather than a fixed quantity.
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Every figure on this page is a range reported in published literature or in a publicly documented study protocol. It is a record of what researchers used, not a recommendation, a therapeutic protocol, or advice. Peptide Intel Hub is an independent publication, sells nothing, and describes these compounds as in-vitro research reagents only.
Each row below describes one body of work. The model and population are part of the figure — a rodent per-kilogram quantity and a human trial quantity are not comparable.
Escalation exists in the protocols to manage gastrointestinal tolerability, not to increase effect faster.
These figures match the published chart for this compound on peptidedosages.com, including the reconstitution volume, resulting concentration, insulin-syringe units and the staged schedule. Educational reference only — not instructions, and not medical advice.
Semaglutide · 10 mg Vial
Semaglutide Dosage calculations for a 10 mg vial use the same once-weekly escalation amounts evaluated in human research and listed in the current injectable product information. Adding 3 mL in this lyophilized-vial calculation produces 3.33 mg/mL, so each U-100 unit contains 33.33 mcg.
| Study Phase | Weekly Amount | U-100 Units | Volume |
|---|---|---|---|
| Weeks 1 to 4 | 0.25 mg | 7.5 units | 0.075 mL |
| Weeks 5 to 8 | 0.5 mg | 15 units | 0.15 mL |
| Weeks 9 to 12 | 1 mg | 30 units | 0.3 mL |
| Weeks 13 to 16 | 1.7 mg | 51 units | 0.51 mL |
| Weeks 17+ | 2.4 mg | 72 units | 0.72 mL |
The same arithmetic for every vial size GLP1 (semaglutide / Ozempic) is supplied in, using a fixed 3 ml of bacteriostatic water. One unit on a U-100 insulin syringe is 0.01 ml, so the unit column below is simply the volume that carries the reported amount. Educational arithmetic only — not instructions, and not medical advice.
GLP1 (semaglutide / Ozempic) · 3 ml bacteriostatic water
| Vial size | Concentration | Per 1 unit |
|---|---|---|
| 5 mg | 1.67 mg/ml | 17 mcg |
| 10 mg | 3.33 mg/ml | 33 mcg |
| 15 mg | 5.00 mg/ml | 50 mcg |
| 20 mg | 6.67 mg/ml | 67 mcg |
| 30 mg | 10.00 mg/ml | 100 mcg |
No single reported amount applies to this compound, so only the concentration and the value of one unit are shown. Only the vial sizes this compound is actually supplied in are shown, and every figure assumes exactly 3 ml of bacteriostatic water. For any other volume, use the reconstitution calculator.
Research vials are typically 5 mg, 10 mg or 15 mg lyophilised. A 10 mg vial in 3 mL of bacteriostatic water gives 3.33 mg/mL, so one U-100 unit carries 33.33 mcg — use the calculator rather than estimating.
Open the reconstitution calculatorThese are the published records the figures on this page are drawn from. Each one describes what researchers administered, in which model or population, and over what period. Quantities reported in a study are specific to that study's design and are not transferable guidance.
Wilding JPH, Batterham RL, Calanna S, et al. · New England Journal of Medicine · 2021 · PMID 33567185
1961 adults with overweight/obesity were randomized to once-weekly subcutaneous semaglutide 2.4 mg or placebo for 68 weeks as an adjunct to lifestyle intervention (STEP 1 trial).
View the recordFrias JP, Davies MJ, Rosenstock J, et al. · New England Journal of Medicine · 2021 · PMID 34170647
Patients with type 2 diabetes were randomized to once-weekly tirzepatide (5, 10, or 15 mg) versus semaglutide 1 mg for 40 weeks (SURPASS-2 trial).
View the recordPeptide Intel Hub is an independent publication and has no affiliation, ownership or commercial relationship with the suppliers listed. We sell nothing and take no payments — links are editorial references only.
Peptide Intel Hub is an independent educational publication. We are not affiliated with, owned by, or the same company as Regena Peptides and Regena.app (regena-peptides.com / regena.app). We do not sell, supply, ship or take payment for any compound. Because readers regularly ask where compounds discussed in published studies can be sourced for laboratory work, we list Regena Peptides and Regena.app as suppliers we have verified and trust — every batch is released with a lot-matched third-party certificate of analysis (HPLC purity and mass-spectrometry identity). Outbound links are marked nofollow/sponsored and are provided to help readers, not to sell.
