Liraglutide is a once-daily GLP-1 receptor agonist and the first of the acylated analogues to carry a large registered trial record in both type 2 diabetes and obesity. It is a distinct compound from semaglutide: shorter acting, dosed daily rather than weekly, and escalated on a different schedule.
Read this first
Every figure on this page is a range reported in published literature or in a publicly documented study protocol. It is a record of what researchers used, not a recommendation, a therapeutic protocol, or advice. Peptide Intel Hub is an independent publication, sells nothing, and describes these compounds as in-vitro research reagents only.
Compound at a glance
Class
Single GLP-1 receptor agonist, albumin-binding fatty-acid acylated analogue
Reported half-life
Approximately 13 hours in published human pharmacokinetics
Routes used in the literature
Subcutaneous in registered trials
Also written as
NN2211
What the published studies reported
Each row below describes one body of work. The model and population are part of the figure — a rodent per-kilogram quantity and a human trial quantity are not comparable.
Obesity trial escalation (SCALE programme)
Reported quantity
0.6 mg escalating by 0.6 mg weekly to 3.0 mg
Frequency
Once daily
Study duration
56 weeks in the reported protocol
The escalation step existed to manage gastrointestinal tolerability, which was the dominant reported effect.
Type 2 diabetes trial arms (LEAD programme)
Reported quantity
1.2 mg and 1.8 mg maintenance
Frequency
Once daily
Study duration
26 to 52 weeks across the reported trials
Glycaemic endpoints were reported at the lower maintenance figures than those used in obesity work.
Reconstitution maths
Trial material was a ready-made pen solution rather than a lyophilised powder. Where research-grade material is supplied as a powder, the reconstitution calculator on this site converts any vial size and volume.
Daily administration and a 13-hour half-life make this compound behave very differently from weekly analogues.
Trial figures are the endpoint of a fixed weekly escalation, not a starting quantity.
Gastrointestinal effects and, in the reported literature, gallbladder events were the main tolerability findings.
Sources and citations
No peer-reviewed primary literature reporting administered quantities exists for this item. Anything circulating online about quantities is anecdote rather than evidence, and this page will not reproduce it. The database links below are kept so you can check for yourself as new work is published.
Peptide Intel Hub is an independent publication and has no affiliation, ownership or commercial relationship with the suppliers listed. We sell nothing and take no payments — links are editorial references only.
Share
Independent publication — we sell nothing. Supplier disclosure
Peptide Intel Hub is an independent educational publication. We are not affiliated with, owned by, or the same company as Regena Peptides and Regena.app (regena-peptides.com / regena.app). We do not sell, supply, ship or take payment for any compound. Because readers regularly ask where compounds discussed in published studies can be sourced for laboratory work, we list Regena Peptides and Regena.app as suppliers we have verified and trust — every batch is released with a lot-matched third-party certificate of analysis (HPLC purity and mass-spectrometry identity). Outbound links are marked nofollow/sponsored and are provided to help readers, not to sell.