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Protocols · Growth Hormone

GHRP-6: literature-reported ranges

GHRP-6 has a long pharmacology literature going back to the 1980s, largely as a tool for probing the ghrelin receptor and pituitary GH release. It is notable for provoking a strong appetite response alongside GH release.

Read this first

Every figure on this page is a range reported in published literature or in a publicly documented study protocol. It is a record of what researchers used, not a recommendation, a therapeutic protocol, or advice. Peptide Intel Hub is an independent publication, sells nothing, and describes these compounds as in-vitro research reagents only.

Compound at a glance

Class
Hexapeptide growth-hormone secretagogue
Reported half-life
Roughly 20–30 minutes
Routes used in the literature
Subcutaneous and intravenous in published pharmacology
Also written as

What the published studies reported

Each row below describes one body of work. The model and population are part of the figure — a rodent per-kilogram quantity and a human trial quantity are not comparable.

Human GH-release pharmacology

Reported quantity
1 µg/kg intravenously as the classic provocative figure
Frequency
Single administration per test
Study duration
Sampling over 120 minutes

1 µg/kg IV is the standard reference figure across the older endocrine literature.

Subcutaneous comparative studies

Reported quantity
100 µg per administration in adult comparative work
Frequency
One to three times daily in multi-day arms
Study duration
Days to a few weeks

Cortisol and prolactin rise alongside GH, unlike with ipamorelin.

Dosage chart

These figures match the published chart for this compound on peptidedosages.com, including the reconstitution volume, resulting concentration, insulin-syringe units and the staged schedule. Educational reference only — not instructions, and not medical advice.

GHRP-6 · 10 mg Vial

GHRP-6 is dosed at 100 mcg–300 mcg daily via subcutaneous injection in educational protocols. A 10 mg vial reconstituted with bacteriostatic water yields about 3.33 mg/mL. This information is for research and educational use only.

Reconstitute
Add 3.0 mL bacteriostatic water → ~ 3.33 mg/mL concentration.
Typical daily range
300–900 mcg total (split into 3 doses with gradual titration).
Easy measuring
At 3.33 mg/mL, 1 unit = 0.01 mL ≈ 33.3 mcg on a U-100 insulin syringe.
Storage
Lyophilized: freeze at −20 °C (−4 °F); after reconstitution, refrigerate at 2–8 °C (35.6–46.4 °F) and use within 7 days.

Standard / Gradual Approach (3 mL = ~3.33 mg/mL)

Week/PhaseDose per Injection (mcg)Units (per injection) (mL)
Weeks 1–2100 mcg3 units (0.03 mL)
Weeks 3–4200 mcg6 units (0.06 mL)
Weeks 5–12300 mcg9 units (0.09 mL)
Source chart on peptidedosages.com

Mixed with 3 ml of bacteriostatic water

The same arithmetic for every vial size GHRP-6 is supplied in, using a fixed 3 ml of bacteriostatic water. One unit on a U-100 insulin syringe is 0.01 ml, so the unit column below is simply the volume that carries the reported amount. Educational arithmetic only — not instructions, and not medical advice.

GHRP-6 · 3 ml bacteriostatic water

Vial sizeConcentrationPer 1 unit300 mcg =900 mcg =
5 mg1.67 mg/ml17 mcg18 units54 units
10 mg3.33 mg/ml33 mcg9.0 units27 units

Unit columns use the range reported for this compound (300 mcg–900 mcg). Only the vial sizes this compound is actually supplied in are shown, and every figure assumes exactly 3 ml of bacteriostatic water. For any other volume, use the reconstitution calculator.

Reconstitution maths

A 5 mg vial in 2.5 mL of bacteriostatic water gives 2 mg/mL; 0.05 mL draws 100 µg.

Open the reconstitution calculator

How to read these figures

  • Non-selective secretagogue: published data shows cortisol and prolactin movement.
  • Receptor desensitisation with repeated exposure is documented in the pharmacology literature.
  • Appetite stimulation is a consistently reported feature, not an incidental one.

Sources and citations

These are the published records the figures on this page are drawn from. Each one describes what researchers administered, in which model or population, and over what period. Quantities reported in a study are specific to that study's design and are not transferable guidance.

  1. [1]
    Oral administration of growth hormone (GH)-releasing peptide stimulates GH secretion in normal men

    Bowers CY, Sartor AO, Reynolds GA, Badger TM. · Journal of Clinical Endocrinology & Metabolism · 1992 · PMID 1592884

    Ten normal men received oral GHRP doses of 30, 100, and 300 micrograms/kg to compare GH-releasing effects with intravenous administration.

    View the record
  2. [2]
    Pharmacokinetic study of Growth Hormone-Releasing Peptide 6 (GHRP-6) in nine male healthy volunteers

    Cabrales A, Gil J, Fernandez E, et al. · European Journal of Pharmaceutical Sciences · 2012 · PMID 23099431

    Nine healthy male volunteers received a single intravenous dose of GHRP-6 to characterize its pharmacokinetic profile.

    View the record
  3. [3]
    Growth hormone-releasing effect of oral growth hormone-releasing peptide 6 (GHRP-6) administration in children with short stature

    Bellone J, Ghizzoni L, Aimaretti G, et al. · European Journal of Endocrinology · 1995 · PMID 7581965

    Children with short stature received oral GHRP-6 to assess GH-releasing effects, establishing an oral dosing regimen in a pediatric population.

    View the record

Search the databases yourself

Read the GHRP-6 research brief

Other growth hormone compounds

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© 2026 Peptide Intel Hub · Marbella · Educational research reference · For in-vitro research use only
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