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Protocols · Growth Hormone

CJC-1295 (no DAC) dosage protocol

Dosage and protocol information sourced exclusively from PeptideDosages.com.

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Dosage and protocol figures on this page are reproduced only from the matching PeptideDosages.com protocol. The 3 ml table is arithmetic based on those source amounts and the listed vial sizes. Educational research only — not instructions or medical advice.

Dosage chart

The dosage amounts and schedules below come only from PeptideDosages.com. Syringe-unit figures are mathematical conversions of those source amounts using exactly 3 ml of bacteriostatic water. Educational reference only — not instructions or medical advice.

CJC-1295 (no DAC) · 5 mg Vial

CJC-1295 NO DAC is dosed at 100 mcg–300 mcg daily via subcutaneous injection in educational protocols.

Typical daily range
100–300 mcg once daily (gradual titration).

Standard / Gradual Approach

WeekDaily Dose (mcg)
Weeks 1–2100 mcg
Weeks 3–4150 mcg
Weeks 5–6200 mcg
Weeks 7–12250–300 mcg

3 ml conversion

5 mg + 3 ml = 1.67 mg/ml. Choose your vial strength to update the units below.

Source doseU-100 syringe
100 mcg6.0 units
150 mcg9.0 units
200 mcg12 units
300 mcg18 units

Mixing note: growth-hormone secretagogues like CJC-1295 (no DAC) are commonly reconstituted with 0.5 ml of acetic acid solution topped up with 2.5 ml of bacteriostatic water (3 ml total). Educational reference only — not instructions.

Source chart on peptidedosages.com

Other growth hormone compounds

CJC-1295 (no DAC) + IpamorelinGHRH analogue + selective ghrelin-receptor agonist blendCJC-1295 with DACGHRH analogue with albumin-binding drug affinity complexGHRP-2Hexapeptide GH secretagogueGHRP-6Hexapeptide growth-hormone secretagogueHexarelinSynthetic hexapeptide GH secretagogueHGH (somatropin, research reference)Recombinant 191-amino-acid human growth hormone
All research protocols

CJC-1295 (no DAC): research background

What the compound is

CJC-1295 is a long-acting analog of Growth Hormone-Releasing Hormone (GHRH) (PMID 16352683). Peptides like CJC-1295 are short chains of amino acids that regulate cellular functions and facilitate biochemical processes (PMID 41476424). It is classified as a growth hormone secretagogue or GHRH analogue (PMID 41490200, PMID 41880199). While some peptide drugs undergo rigorous approval processes, CJC-1295 is among a group of unapproved compounds that operate largely outside of regulatory oversight, often marketed directly to patients (PMID 41966639, PMID 42123471).

How it is thought to work

CJC-1295 is designed to prolong the stimulation of growth hormone (GH) and insulin-like growth factor I (IGF-I) secretion (PMID 16352683). GHRH, which CJC-1295 mimics, typically has a short duration of action, limiting its therapeutic use (PMID 16352683). As a growth hormone secretagogue, CJC-1295 activates IGF-1 signaling (PMID 41490200). In the context of gerontology, CJC-1295 is noted for its role in growth hormone modulation (PMID 42021992).

What laboratory and animal studies report

Preclinical studies on various peptides, including CJC-1295, are generally promising, but human clinical trial data are often lacking (PMID 41490200, PMID 41966639). In animal models (specifically murine models), CJC-1295 combined with ipamorelin showed significantly improved maximum tetanic tension in cases of glucocorticoid-induced muscle loss (PMID 41476424). Overall, 67% of identified publications concerning emerging peptides for musculoskeletal recovery and enhancement utilized preclinical animal models, often rats, showing unique mechanisms with promising, though variable, effects on various tissues (PMID 42578445).

Human evidence so far

In a study involving healthy adults, subcutaneous administration of CJC-1295 resulted in sustained, dose-dependent increases in mean plasma GH concentrations by 2- to 10-fold for 6 days or more, and in mean plasma IGF-I concentrations by 1.5- to 3-fold for 9-11 days after a single injection (PMID 16352683). After multiple doses, mean IGF-I levels remained above baseline for up to 28 days (PMID 16352683). The estimated half-life of CJC-1295 in humans was 5.8-8.1 days (PMID 16352683). The study concluded that CJC-1295 was safe and relatively well tolerated in healthy adults, particularly at doses of 30 or 60 microg/kg, with no serious adverse reactions reported (PMID 16352683). However, beyond this study, rigorous human safety data for many unapproved peptides, including CJC-1295, are scarce (PMID 41966639, PMID 42578445).

Open questions and limitations

Despite promising findings in animal studies, the claimed benefits of emerging peptide supplements like CJC-1295 for musculoskeletal recovery and performance remain largely unsubstantiated by current human trials (PMID 42578445). There is a significant lack of clinical trials and rigorous human safety data (PMID 41490200, PMID 41966639). Studies on peptide use in sport often examine therapeutic applications under controlled dosing, which differs from common bodybuilding practices (PMID 41880199). Significant knowledge gaps exist regarding optimal dosing regimens, combination therapy effects, and biomarkers for monitoring efficacy (PMID 42021992). The peptide supplement market is rapidly growing, often driven by marketing claims that are not backed by efficacy or safety data (PMID 42578445). Peptides such as CJC-1295 are often promoted as safer alternatives to other performance enhancers, but they remain experimental substances with poorly defined long-term risks (PMID 41880199).

Key terms explained

Growth Hormone (GH): A hormone that stimulates growth, cell reproduction, and cell regeneration (PMID 16352683). Insulin-like Growth Factor I (IGF-I): A hormone structurally similar to insulin, playing a role in childhood growth and continuing to have anabolic effects in adults (PMID 16352683, PMID 41490200). Growth Hormone-Releasing Hormone (GHRH): A hypothalamic peptide that stimulates the release of growth hormone from the pituitary gland (PMID 16352683).

Studies cited in this section

Summarised from the PubMed abstracts listed above. Educational reference only — not medical advice or instructions.

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