Protocols · Cognitive
DSIP was isolated in the 1970s from rabbit cerebral venous blood during induced sleep. The human literature is small, old, and inconsistent — several controlled studies failed to find the sleep effect the name promises.
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Every figure on this page is a range reported in published literature or in a publicly documented study protocol. It is a record of what researchers used, not a recommendation, a therapeutic protocol, or advice. Peptide Intel Hub is an independent publication, sells nothing, and describes these compounds as in-vitro research reagents only.
Each row below describes one body of work. The model and population are part of the figure — a rodent per-kilogram quantity and a human trial quantity are not comparable.
25 nmol/kg is the figure carried across most of the human work.
Effects on withdrawal scores were reported more consistently than effects on sleep architecture.
These figures match the published chart for this compound on peptidedosages.com, including the reconstitution volume, resulting concentration, insulin-syringe units and the staged schedule. Educational reference only — not instructions, and not medical advice.
DSIP · 10 mg Vial
DSIP (Delta Sleep-Inducing Peptide) is dosed at 100 mcg–300 mcg daily via subcutaneous injection in educational protocols, usually before bedtime. A 10 mg vial reconstituted with bacteriostatic water yields about 3.33 mg/mL. This information is for research and educational use only.
| Week | Daily Dose (mcg) | Units (per injection) (mL) |
|---|---|---|
| Week 1 | 100 mcg | 3 units (0.03 mL) |
| Week 2 | 150 mcg | 5 units (0.05 mL) |
| Week 3 | 200 mcg | 6 units (0.06 mL) |
| Weeks 4–8 | 250–300 mcg | 8–9 units (0.08–0.09 mL) |
The same arithmetic for every vial size DSIP is supplied in, using a fixed 3 ml of bacteriostatic water. One unit on a U-100 insulin syringe is 0.01 ml, so the unit column below is simply the volume that carries the reported amount. Educational arithmetic only — not instructions, and not medical advice.
DSIP · 3 ml bacteriostatic water
| Vial size | Concentration | Per 1 unit | 100 mcg = | 300 mcg = |
|---|---|---|---|---|
| 2 mg | 0.67 mg/ml | 7 mcg | 15 units | 45 units |
| 5 mg | 1.67 mg/ml | 17 mcg | 6.0 units | 18 units |
| 10 mg | 3.33 mg/ml | 33 mcg | 3.0 units | 9.0 units |
| 15 mg | 5.00 mg/ml | 50 mcg | 2.0 units | 6.0 units |
Unit columns use the range reported for this compound (100 mcg–300 mcg). Only the vial sizes this compound is actually supplied in are shown, and every figure assumes exactly 3 ml of bacteriostatic water. For any other volume, use the reconstitution calculator.
A 5 mg vial in 2 mL of bacteriostatic water gives 2.5 mg/mL. The literature uses nanomole units, so conversion via the ~849 g/mol molecular weight is required.
Open the reconstitution calculatorThese are the published records the figures on this page are drawn from. Each one describes what researchers administered, in which model or population, and over what period. Quantities reported in a study are specific to that study's design and are not transferable guidance.
Schneider-Helmert D, Gnirss F, Monnier M, Schenker J, Schoenenberger GA · Int J Neurosci / Pharmacopsychiatria · 1981 · PMID 6895513
Six healthy volunteers received slow intravenous infusions of DSIP at a dose of 25 nmol/kg in the morning in a double-blind crossover study assessing effects on sleep behavior.
View the record(Study of DSIP in chronic insomniacs) · Pharmacopsychiatry · 1987 · PMID 3583493
Chronic insomniac patients received intravenous DSIP at 25 nmol/kg or placebo over four nights in a double-blind crossover design, with polysomnographic assessment of sleep parameters.
View the recordKaeser HE · Eur Neurol · 1984 · PMID 6391926
Seven patients with severe insomnia received a series of 10 injections of DSIP in an open-label study, with most patients experiencing normalized sleep for 3-7 months of follow-up.
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Peptide Intel Hub is an independent educational publication. We are not affiliated with, owned by, or the same company as Regena Peptides and Regena.app (regena-peptides.com / regena.app). We do not sell, supply, ship or take payment for any compound. Because readers regularly ask where compounds discussed in published studies can be sourced for laboratory work, we list Regena Peptides and Regena.app as suppliers we have verified and trust — every batch is released with a lot-matched third-party certificate of analysis (HPLC purity and mass-spectrometry identity). Outbound links are marked nofollow/sponsored and are provided to help readers, not to sell.
