Protocols · Hormone
Oxytocin has two almost separate literatures: a large obstetric one using intravenous infusion, and a large social-neuroscience one using intranasal administration. The intranasal behavioural literature converged on a single figure, and it is also the literature with the most serious replication problems.
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Every figure on this page is a range reported in published literature or in a publicly documented study protocol. It is a record of what researchers used, not a recommendation, a therapeutic protocol, or advice. Peptide Intel Hub is an independent publication, sells nothing, and describes these compounds as in-vitro research reagents only.
Each row below describes one body of work. The model and population are part of the figure — a rodent per-kilogram quantity and a human trial quantity are not comparable.
24 IU became the field-standard figure largely by convention rather than by dose-finding.
Longer arms report attenuation of the acute effects.
These figures match the published chart for this compound on peptidedosages.com, including the reconstitution volume, resulting concentration, insulin-syringe units and the staged schedule. Educational reference only — not instructions, and not medical advice.
Oxytocin · 10 mg Vial
Oxytocin is dosed at 100 mcg–500 mcg daily in educational protocols, administered subcutaneously or intranasally. A 10 mg vial reconstituted with bacteriostatic water yields about 3.33 mg/mL. This information is for research and educational use only.
| Week | Daily Dose (mcg) | Units (per injection) (mL) |
|---|---|---|
| Weeks 1–2 | 100 mcg | 3 units (0.03 mL) |
| Weeks 3–4 | 200 mcg | 6 units (0.06 mL) |
| Weeks 5–6 | 300 mcg | 9 units (0.09 mL) |
| Weeks 7–8 | 400 mcg | 12 units (0.12 mL) |
| Weeks 9–12 | 500 mcg | 15 units (0.15 mL) |
The same arithmetic for every vial size Oxytocin is supplied in, using a fixed 3 ml of bacteriostatic water. One unit on a U-100 insulin syringe is 0.01 ml, so the unit column below is simply the volume that carries the reported amount. Educational arithmetic only — not instructions, and not medical advice.
Oxytocin · 3 ml bacteriostatic water
| Vial size | Concentration | Per 1 unit | 100 mcg = | 500 mcg = |
|---|---|---|---|---|
| 2 mg | 0.67 mg/ml | 7 mcg | 15 units | 75 units |
| 5 mg | 1.67 mg/ml | 17 mcg | 6.0 units | 30 units |
Unit columns use the range reported for this compound (100 mcg–500 mcg). Only the vial sizes this compound is actually supplied in are shown, and every figure assumes exactly 3 ml of bacteriostatic water. For any other volume, use the reconstitution calculator.
Research powder is commonly 2 mg or 10 mg. 1 IU is approximately 1.67 µg, so 10 mg is roughly 6,000 IU — a mass-labelled vial and an IU-labelled one are easy to confuse by orders of magnitude.
Open the reconstitution calculatorThese are the published records the figures on this page are drawn from. Each one describes what researchers administered, in which model or population, and over what period. Quantities reported in a study are specific to that study's design and are not transferable guidance.
Sikich L, Kolevzon A, King BH, et al. · N Engl J Med · 2021 · DOI 10.1056/NEJMoa2103583
Children and adolescents with ASD received intranasal oxytocin, titrated up to a maximum of 48 IU/day, over a 24-week placebo-controlled trial.
View the recordGuastella AJ, Boulton K, Whitehouse A, et al. · Mol Psychiatry · 2022 · DOI 10.1038/s41380-022-01845-8
Young children with autism received intranasal oxytocin twice daily (dose titrated by weight, up to 24 IU/dose) for 5 weeks.
View the recordEinfeld SL, Hickie IB, Davenport TA, Guastella AJ. · Mol Psychiatry · 2015 · PMCID PMC4995545
Young children with autism received intranasal oxytocin twice daily for 5 weeks in a randomized crossover design assessing social responsiveness.
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Peptide Intel Hub is an independent educational publication. We are not affiliated with, owned by, or the same company as Regena Peptides and Regena.app (regena-peptides.com / regena.app). We do not sell, supply, ship or take payment for any compound. Because readers regularly ask where compounds discussed in published studies can be sourced for laboratory work, we list Regena Peptides and Regena.app as suppliers we have verified and trust — every batch is released with a lot-matched third-party certificate of analysis (HPLC purity and mass-spectrometry identity). Outbound links are marked nofollow/sponsored and are provided to help readers, not to sell.
