Thymalin — Literature-Reported Ranges & Study Protocols

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Every figure on this page is a range reported in published literature or in a publicly documented study protocol. It is a record of what researchers used, not a recommendation, a therapeutic protocol, or advice. Peptide Intel Hub is an independent publication, sells nothing, and describes these compounds as in-vitro research reagents only.

Compound at a glance

Class: Thymic peptide extract preparation
Reported half-life: Not characterised — it is a peptide fraction, not a single molecule
Routes used in the literature: Intramuscular in the published Russian work
Also written as: —

What the published studies reported

Each row below describes one body of work. The model and population are part of the figure — a rodent per-kilogram quantity and a human trial quantity are not comparable.

Russian clinical and cohort protocols

Reported quantity: 10 mg per administration
Frequency: Once daily
Study duration: 5–10 day courses, repeated once or twice yearly

The repeated short-course structure is consistent across this literature.

Immune-parameter studies

Reported quantity: 5–20 mg per day depending on the indication studied
Frequency: Once daily
Study duration: 5–14 days

T-lymphocyte subsets are the usual measured endpoint.

Mixed with 3 ml of bacteriostatic water

The same arithmetic for every vial size Thymalin is supplied in, using a fixed 3 ml of bacteriostatic water. One unit on a U-100 insulin syringe is 0.01 ml, so the unit column below is simply the volume that carries the reported amount. Educational arithmetic only — not instructions, and not medical advice.

Thymalin · 3 ml bacteriostatic water

Vial size	Concentration	Per 1 unit
10 mg	3.33 mg/ml	33 mcg
100 mg	33.33 mg/ml	333 mcg

No single reported amount applies to this compound, so only the concentration and the value of one unit are shown. Only the vial sizes this compound is actually supplied in are shown, and every figure assumes exactly 3 ml of bacteriostatic water. For any other volume, use the reconstitution calculator.

Reconstitution maths

Supplied as a 10 mg lyophilised vial, reconstituted in 1–2 mL of sterile saline or bacteriostatic water in the source protocols.

Open the reconstitution calculator

How to read these figures

As an extract, batch composition is inherently variable between manufacturers.
Bovine-derived material carries sourcing and regulatory considerations that synthetic peptides do not.
The long-term cohort claims come from a single research tradition and have not been independently replicated.

Sources and citations

These are the published records the figures on this page are drawn from. Each one describes what researchers administered, in which model or population, and over what period. Quantities reported in a study are specific to that study's design and are not transferable guidance.

[1]
Peptides of pineal gland and thymus prolong human life
Khavinson VK · Neuro Endocrinol Lett · 2002 · PMID 14523363
Elderly patients received courses of thymic peptide bioregulator Thymalin (and pineal peptide Epithalamin) injections annually to assess effects on mortality and aging markers.
View the record
[2]
Peptide Drug Thymalin Regulates Immune Status in Severe COVID-19 Older Patients
Kuznik BI, Khavinson V, Shapovalov KG, et al. · Adv Gerontol · 2021 · DOI 10.1134/S2079057021040068
Older patients with severe COVID-19 received intramuscular Thymalin injections over a defined course to evaluate immune status regulation.
View the record
[3]
The Use of Thymalin for Immunocorrection and Molecular Aspects of Biological Activity
Linkova NS, Chalisova NI, Ivko OM, et al. · Biol Bull Rev · 2021 · DOI 10.1134/S2079086421040046
Review describing clinical dosing regimens (short intramuscular courses) of Thymalin used for immunocorrection in various patient populations.
View the record

Search the databases yourself

Read the Thymalin research brief

Other immune compounds

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All research protocols

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