BPC-157 — Literature-Reported Ranges & Study Protocols

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Every figure on this page is a range reported in published literature or in a publicly documented study protocol. It is a record of what researchers used, not a recommendation, a therapeutic protocol, or advice. Peptide Intel Hub is an independent publication, sells nothing, and describes these compounds as in-vitro research reagents only.

Compound at a glance

Class: Synthetic pentadecapeptide (gastric origin)
Reported half-life: Short in plasma (minutes); tissue effects reported well beyond clearance
Routes used in the literature: Reported in the literature as intraperitoneal, subcutaneous, oral and topical in animal models
Also written as: —

What the published studies reported

Each row below describes one body of work. The model and population are part of the figure — a rodent per-kilogram quantity and a human trial quantity are not comparable.

Rodent tendon and ligament transection models

Reported quantity: 10 µg/kg body weight (most common reported figure)
Frequency: Once daily
Study duration: 10–14 days in most published protocols

10 µg/kg is the single most repeated figure across Sikiric-group injury papers.

Rodent gastrointestinal and colitis models

Reported quantity: 10 ng/kg to 10 µg/kg (a 1000-fold reported window)
Frequency: Once daily, or in drinking water in oral arms
Study duration: 7–21 days

Gut studies frequently report the low nanogram arm performing comparably to the microgram arm.

Rodent nerve-crush and CNS models

Reported quantity: 10 µg/kg
Frequency: Once daily
Study duration: Up to 4 weeks in longer recovery studies

Longer observation windows are used because functional recovery endpoints take weeks.

Dosage chart

These figures match the published chart for this compound on peptidedosages.com, including the reconstitution volume, resulting concentration, insulin-syringe units and the staged schedule. Educational reference only — not instructions, and not medical advice.

BPC-157 · 10 mg Vial

BPC-157 is dosed at 200 mcg–600 mcg daily via subcutaneous injection in educational protocols. A 10 mg vial reconstituted with bacteriostatic water yields about 3.33 mg/mL. This information is for research and educational use only.

Reconstitute: Add 3.0 mL bacteriostatic water → 3.33 mg/mL concentration.
Typical daily range: 200–600 mcg once daily (gradual titration).
Easy measuring: At 3.33 mg/mL, 1 unit = 0.01 mL ≈ 33.3 mcg on a U-100 insulin syringe.
Storage: Lyophilized: freeze at −20 °C (−4 °F); after reconstitution, refrigerate at 2–8 °C (35.6–46.4 °F); avoid freeze–thaw cycles.

Standard / Gradual Approach (3 mL = ~3.33 mg/mL)

Week	Daily Dose (mcg)	Units (per injection) (mL)
Weeks 1–2	200 mcg (0.2 mg)	6 units (0.06 mL)
Weeks 3–4	400 mcg (0.4 mg)	12 units (0.12 mL)
Weeks 5–8+	600 mcg (0.6 mg)	18 units (0.18 mL)

Source chart on peptidedosages.com

Mixed with 3 ml of bacteriostatic water

The same arithmetic for every vial size BPC-157 is supplied in, using a fixed 3 ml of bacteriostatic water. One unit on a U-100 insulin syringe is 0.01 ml, so the unit column below is simply the volume that carries the reported amount. Educational arithmetic only — not instructions, and not medical advice.

BPC-157 · 3 ml bacteriostatic water

Vial size	Concentration	Per 1 unit	200 mcg =	600 mcg =
5 mg	1.67 mg/ml	17 mcg	12 units	36 units
10 mg	3.33 mg/ml	33 mcg	6.0 units	18 units

Unit columns use the range reported for this compound (200 mcg–600 mcg). Only the vial sizes this compound is actually supplied in are shown, and every figure assumes exactly 3 ml of bacteriostatic water. For any other volume, use the reconstitution calculator.

Reconstitution maths

Lyophilised 5 mg and 10 mg vials are the common research presentations. Reconstituting a 5 mg vial with 2 mL of bacteriostatic water gives 2500 µg/mL; with 5 mL it gives 1000 µg/mL. Use the reconstitution calculator on this site to convert a vial into concentration and draw volume.

Open the reconstitution calculator

How to read these figures

Every published quantity is per kilogram of animal body weight — species scaling is not a simple multiplication.
Oral, intraperitoneal and subcutaneous arms are not interchangeable; bioavailability differs by an order of magnitude.
Purity matters more than quantity: request lot-matched HPLC purity and mass-spectrometry identity before any work.

Sources and citations

These are the published records the figures on this page are drawn from. Each one describes what researchers administered, in which model or population, and over what period. Quantities reported in a study are specific to that study's design and are not transferable guidance.

[1]
Gastric pentadecapeptide BPC 157 accelerates healing of transected rat Achilles tendon and in vitro stimulates tendocytes growth
Krivic A, Anic T, Seiwerth S, et al. · J Orthop Res · 2003 · DOI 10.1016/S0736-0266(03)00110-4
Rats with transected Achilles tendons received BPC 157 (given intraperitoneally/in drinking water at microgram-per-kilogram doses) daily, accelerating tendon healing versus controls.
View the record
[2]
Achilles Detachment in Rat and Stable Gastric Pentadecapeptide BPC 157: Promoted Tendon-to-Bone Healing and Opposed Corticosteroid Aggravation
Krivic A, Anic T, Seiwerth S, Huljev D, Sikiric P · J Orthop Res · 2006 · DOI 10.1002/jor.20096
Rats with Achilles tendon detachment were dosed with BPC 157 (µg/kg range, intraperitoneal) daily, promoting tendon-to-bone healing and counteracting corticosteroid-induced impairment.
View the record

Search the databases yourself

Read the BPC-157 research brief

Other regenerative compounds

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All research protocols

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