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Protocols · Growth Hormone

GHRP-2: literature-reported ranges

GHRP-2 is registered in Japan as a diagnostic agent for GH deficiency, which gives it a defined and well-documented human figure — a rarity in this field.

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Every figure on this page is a range reported in published literature or in a publicly documented study protocol. It is a record of what researchers used, not a recommendation, a therapeutic protocol, or advice. Peptide Intel Hub is an independent publication, sells nothing, and describes these compounds as in-vitro research reagents only.

Compound at a glance

Class
Hexapeptide GH secretagogue
Reported half-life
Approximately 30 minutes
Routes used in the literature
Intravenous in diagnostic use; subcutaneous in research designs
Also written as
Pralmorelin

What the published studies reported

Each row below describes one body of work. The model and population are part of the figure — a rodent per-kilogram quantity and a human trial quantity are not comparable.

Registered diagnostic testing

Reported quantity
100 µg intravenously as a bolus
Frequency
Single administration
Study duration
Sampling at 15, 30, 45 and 60 minutes

This is a licensed diagnostic figure, not a multi-week protocol.

Paediatric and adult dose-ranging

Reported quantity
0.1–1.0 µg/kg
Frequency
Single administration per test
Study duration
60–120 minutes of sampling

GH response saturates toward the top of this window.

Multi-week appetite and IGF-1 research arms

Reported quantity
Around 100 µg per administration
Frequency
One to three times daily
Study duration
2–16 weeks

Appetite stimulation is a consistent reported feature across these arms.

Dosage chart

These figures match the published chart for this compound on peptidedosages.com, including the reconstitution volume, resulting concentration, insulin-syringe units and the staged schedule. Educational reference only — not instructions, and not medical advice.

GHRP-2 · 10 mg Vial

GHRP-2 is dosed at 100 mcg–300 mcg daily via subcutaneous injection in educational protocols. A 10 mg vial reconstituted with bacteriostatic water yields about 3.33 mg/mL. This information is for research and educational use only.

Reconstitute
Add 3.0 mL bacteriostatic water → ~ 3.33 mg/mL concentration.
Typical daily range
100–300 mcg once daily (gradual titration).
Easy measuring
At 3.33 mg/mL, 1 unit ≈ 33.3 mcg on a U‑100 insulin syringe.
Storage
Lyophilized: freeze at −20 °C (−4 °F); after reconstitution, refrigerate at 2–8 °C (35.6–46.4 °F); avoid freeze–thaw cycles.

Standard / Gradual Approach (3 mL = ~3.33 mg/mL)

WeekDaily Dose (mcg)Units (per injection) (mL)
Weeks 1–2100 mcg (0.1 mg)3 units (0.03 mL)
Weeks 3–4150 mcg (0.15 mg)4.5 units (0.045 mL)
Weeks 5–8200 mcg (0.2 mg)6 units (0.06 mL)
Weeks 9–12 (optional)250–300 mcg (0.25–0.3 mg)7.5–9 units (0.075–0.09 mL)
Source chart on peptidedosages.com

Mixed with 3 ml of bacteriostatic water

The same arithmetic for every vial size GHRP-2 is supplied in, using a fixed 3 ml of bacteriostatic water. One unit on a U-100 insulin syringe is 0.01 ml, so the unit column below is simply the volume that carries the reported amount. Educational arithmetic only — not instructions, and not medical advice.

GHRP-2 · 3 ml bacteriostatic water

Vial sizeConcentrationPer 1 unit100 mcg =300 mcg =
5 mg1.67 mg/ml17 mcg6.0 units18 units
10 mg3.33 mg/ml33 mcg3.0 units9.0 units

Unit columns use the range reported for this compound (100 mcg–300 mcg). Only the vial sizes this compound is actually supplied in are shown, and every figure assumes exactly 3 ml of bacteriostatic water. For any other volume, use the reconstitution calculator.

Reconstitution maths

A 5 mg vial in 2.5 mL of bacteriostatic water gives 2 mg/mL; 0.05 mL draws 100 µg.

Open the reconstitution calculator

How to read these figures

  • Diagnostic single-administration figures are frequently misquoted online as ongoing schedules.
  • Cortisol and prolactin rise alongside GH, as with GHRP-6.
  • Receptor desensitisation applies to the whole hexapeptide class.

Sources and citations

These are the published records the figures on this page are drawn from. Each one describes what researchers administered, in which model or population, and over what period. Quantities reported in a study are specific to that study's design and are not transferable guidance.

  1. [1]
    GH-releasing hormone and GH-releasing peptide-6 for diagnostic testing in GH-deficient adults

    Popovic V, Leal A, Micic D, et al. · European Journal of Endocrinology · 2001 · PMID 11322505

    Older men and women with decreased GH secretion received acute and chronic GHRP-2 administration to assess GH/IGF-1 responses compared with GHRH.

    View the record
  2. [2]
    A simple diagnostic test using GH-releasing peptide-2 in adult GH deficiency

    Bonert VS, Kennedy L, Michalik JL, et al. · Journal of Endocrinological Investigation · 2007 · PMID 17609397

    Seventy-seven healthy subjects and GH-deficient adults were given a validated intravenous 1 microgram/kg GHRP-2 bolus dose as a diagnostic stimulation test for GH deficiency.

    View the record
  3. [3]
    Growth hormone-releasing effect of oral growth hormone-releasing peptide 2 in children with short stature

    Mericq V, Cassorla F, Bowers CY, et al. · European Journal of Endocrinology · 1998 · PMID 9661608

    GH-deficient children were treated for eight months with graded doses of a GH-releasing peptide to evaluate sustained GH secretion and growth effects.

    View the record

Search the databases yourself

Read the GHRP-2 research brief

Other growth hormone compounds

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© 2026 Peptide Intel Hub · Marbella · Educational research reference · For in-vitro research use only
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